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Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.1 High systolic blood pressure (SBP) remains one of the top risk factors for CVD burden globally.2 Despite being a modifiable risk factor, hypertension (HTN) remains largely undiagnosed and untreated due to inadequate screening, poor awareness and lack of treatment adherence.3 Globally, HTN is undiagnosed in about 46% […]

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16 Results Found for “Atrio-ventricular synchrony”

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As 2025 draws to a close, we’re celebrating another remarkable year of growth, collaboration and innovation at touchCARDIO. From thought-provoking expert interviews and peer-reviewed research to dynamic conference coverage and an expanding portfolio of medical education, this year has been defined by meaningful conversations and impactful learning. We’ve had the privilege of engaging with leading clinicians, researchers and partner societies across the globe - bringing together diverse voices to support the cardiology community with timely, accessible and authoritative content. As we reflect on the past 12 months, we’re proud to highlight the moments, milestones and stories that shaped our year.

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Welcome to this issue of Heart International. As ever, we aim to provide our readers with the latest developments, insights, and evidence-based discussions in cardiovascular care. This edition is particularly poignant, as we begin with a heartfelt tribute to an ...

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The first-in-human implantation of a leadless pacing system occurred already more than 10 years ago.1 The first-generation ventricular leadless pacemaker could provide only asynchronous ventricular pacing (ventricular, ventricular, inhibited [VVI], or ventricular, ventricular, inhibited, rate response [VVIR]), limiting its indications to ...

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For decades, right ventricular pacing (RVP) has been the leading pacing technique and has been proven to be effective in treating patients with symptomatic bradycardia. However, dyssynchrony caused by non-physiological ventricular activation results in pacing-induced cardiomyopathy occurs in approximately 15% of ...

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The OptiVALL study aimed to assess the atrioventricular synchronous pacing capabilities of the Micra AV device, and to describe what programming changes are needed. In this touchCARDIO interview, we speak with Dr Sem Briongos Figuero (Hospital Infanta Leonor, Madrid, Spain) ...

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Coverage from: EHRA Highlights

The MARVEL 2 trial studied atrioventricular synchronous pacing in patients with a Micra leadless ventricular pacemaker. In this touchCARDIO interview, we speak with Dr Sem Briongos Figuero (Hospital Infanta Leonor, Madrid, Spain) to discuss the trials studying atrioventricular synchrony and their ...

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Conventionally, according to the European Society of Cardiology pacing and cardiac resynchronization therapy (CRT) guidelines, patients with clinical heart failure and an echocardiographically measured left ventricular (LV) ejection fraction of <35% are considered for CRT implantation or standard right ventricular (...

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Alwin Zweerink, Elise Bakelants, Cornelis P Allaart

Over the past years, several reports have drawn attention to the need to consider sex-specific differences in cardiac resynchronisation therapy (CRT). Most importantly, there is growing concern on the underrepresentation of women in CRT landmark trials which laid the foundation ...

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Authors: N Wijesuriya (Presenting Author) - Kings College, London, London, UK; M Strocchi - Kings College, London, London, UK; V Mehta - Kings College, London, London, UK; F De Vere - Kings College, London, London, UK; S Howell - Kings College, London, London, UK; JM Behar - Kings College, London, London, UK; P Bosco - Guys and St Thomas’s NHS Foundation Trust, London, UK; SA Niederer - Kings College, London, London, UK; CA Rinaldi - Kings College, London, London, UK

Introduction: Leadless left ventricular (LV) endocardial pacing with the WiSE-CRT System (EBR Systems Inc) is a novel treatment in the field of cardiac resynchronization therapy (CRT). The system was designed to provide lateral wall LV pacing (LVP) in response to ...

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AA Miyazawa (Presenting Author) – Imperial College London, London, UK; D Keene – Imperial College London, London, UK; AD Arnold – Imperial College London, London, UK; JS Mohal – Imperial College London, London, UK; A Naraen – Imperial College London, London, UK; N Ali – Imperial College London, London, UK; MJ Shun-Shin – Imperial College London, London, UK; DC Lefroy – Imperial College Healthcare NHS Trust, London, UK; PB Lim – Imperial College London, London, UK; FS Ng – Imperial College London, London, UK; M Koa-Wing – Imperial College Healthcare NHS Trust, London, UK; N Qureshi – Imperial College London, London, UK; NWF Linton – Imperial College London, London, UK; NS Peters – Imperial College London, London, UK; P Kanagaratnam – Imperial College London, London, UK; DP Francis – Imperial College London, London, UK; ZI Whinnett – Imperial College London, London, UK

Introduction: Implantable cardioverter defibrillators (ICDs) reduce mortality in people at risk of sudden cardiac death. During ventricular tachycardias (VT), cardiac output is reduced due to fast heart rates reducing diastolic filling time, loss of atrio-ventricular synchrony and loss of bi-ventricular ...

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It is well established that chronic right ventricular apical pacing may have an adverse effect on left ventricular systolic function,1,2 leading, in the long term, to adverse clinical outcomes such as heart failure,3 atrial fibrillation4,5 and even death.6 As an ...

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Current use of QRS duration in cardiac resynchronization therapy Cardiac resynchronization therapy (CRT) is an established therapeutic option in patients with symptomatic systolic heart failure concomitant with electrical dyssynchrony.1–3 Patients with a wide QRS (≥120 ms), especially those with a left ...

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S Brown (Presenting Author) – Musgrove Park Hospital, Taunton; M Jones – Musgrove Park Hospital, Taunton; O Clayton – Musgrove Park Hospital, Taunton; G Furniss – Musgrove Park Hospital, Taunton; M Dayer – Musgrove Park Hospital, Taunton

Introduction: The Biotronik DX lead is a defibrillator lead that has been in use since 2010. It offers atrial sensing from the floating dipole as it passes through the atrium. This improves tachyarrhythmia discrimination and can provide atrioventricular synchrony in patients ...

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A Naraen (Presenting Author) – St Helen’s Knowlsely Teaching Hospitals Trust, Liverpool; AD Arnold – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; MJ Shun-Shin – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; N Ali – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; D Keene – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; JP Howard – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; J Chow – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; IJ Wright – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; FS Ng – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; NA Qureshi – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; M Koa-Wing – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; DC Lefroy – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; NWF Linton – Department of Bioengineering, Imperial College London, Hammersmith Hospital, London; PB Lim – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; NS Peters – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; A Muthumala – Cardiology Department, North Middlesex University Hospital NHS Trust; Cardiology Department, St Bartholomew’s Hospital, Barts Health NHS Trust, London; M Tanner – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; KA Ellenbogen – Division of Cardiac Electrophysiology, Virginia Commonwealth University, Richmond; P Kanagaratnam – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; DP Francis – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; ZI Whinnett – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London

Background: It is assumed that resynchronisation of the ventricles in patients with heart failure and left bundle branch block (LBBB) delivers the most benefit in biventricular pacing (BVP). Because cardiac resynchronisation therapy (CRT) with BVP both shortens atrioventricular delay and ...

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PH Waddingham (Presenting Author) - St Bartholomew’s Hospital, Barts Health NHS Trust, London; M Orini - St Bartholomew’s Hospital, Barts Health NHS Trust, London; J Mangual - Abbott, Sylmar; A Muthumala - St Bartholomew’s Hospital, Barts Health NHS Trust, London; S Sporton - St Bartholomew’s Hospital, Barts Health NHS Trust, London; PD Lambiase - St Bartholomew’s Hospital, Barts Health NHS Trust, London; AWC Chow - St Bartholomew’s Hospital, Barts Health NHS Trust, London

Background: Cardiac resynchronization therapy (CRT) with MultiPoint Pacing (MPP) can improve electrical resynchronization of the left ventricle (LV) compared to conventional CRT. The SyncAV™ algorithm dynamically combines intrinsic atrioventricular (AV) conduction with pacing, improving electrical synchrony. The study objectives included ...

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Introduction: Post cardiac surgery, the management of haemodynamics in the ITU can be significantly influenced by appropriately programmed, temporary dual chamber pacing. More specifically, there should be a high importance placed on maintaining atrio-ventricular synchrony in patients who are already ...

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