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Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.1 High systolic blood pressure (SBP) remains one of the top risk factors for CVD burden globally.2 Despite being a modifiable risk factor, hypertension (HTN) remains largely undiagnosed and untreated due to inadequate screening, poor awareness and lack of treatment adherence.3 Globally, HTN is undiagnosed in about 46% […]

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24 Results Found for “cardiac computed tomography (CT) angiography, ”

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Doctor holding glowing holographic human anatomical heart. Medical illustration, heart diseases, heart health
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Native valve infective endocarditis (IE) is rare, with an incidence of 3–7 cases per 100,000 person-years.1,2 Cardiac structural complications from local infection extension include valvular destruction, peri-annular abscess and fistula formation. Left ventricular pseudoaneurysm (LVP) from IE is exceedingly rare, occurring in &...

Electrocardiogram line, EKG heartbeat rhythm display on a medical monitor, illuminated by blue neon light against a dark grid, representing a health concept.
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Sudden cardiac arrest (SCA) in young adults (typically defined as individuals younger than 40 years) has emerged as an important yet under-recognized public health concern. Recent estimates suggest an incidence of approximately 1–4 cases per 100,000 person-years, underscoring the clinical and epidemiological relevance ...

Pressure measurement of hypertension in elderly woman sitting on couch, young woman nurse or caregiver care checking, measuring heart, blood by using sphygmomanometer monitor
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Hypertension affects over 1.4 billion adults worldwide and remains the leading modifiable risk factor for global cardiovascular (CV) morbidity and mortality. It is responsible for an estimated 10.8 million deaths annually and contributes significantly to the global burden of ischaemic heart disease, ...

First Asymptomatic Gene Carrier Dosed in Pioneering Trial for Rare ATTRv Amyloidosis: the ACT-EARLY Study
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Cardiovascular medicine in 2025 has been marked by rapid innovation and meaningful shifts in clinical practice. In this year-in-review, touchCARDIO brings together expert reflections highlighting paradigm-changing trial data, the emergence of pulsed field ablation and conduction system pacing, advances in imaging and prevention, and the accelerating integration of artificial intelligence. Collectively, these perspectives underscore a field evolving toward more precise, technology-enabled and preventive cardiovascular care, while emphasising the need to translate scientific progress into improved outcomes for patients worldwide.

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Epicardial adipose tissue (EAT) is a fat collection directly adjacent to the myocardium and coronary vasculature, lacking any separation and sharing the same circulation.1,2 This anatomy enables direct signalling between EAT and the surrounding tissue, positioning EAT as a central ...

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Cardiovascular disease (CVD) continues to be the leading cause of death on a global scale. Nearly 18 million people died from CVD in 2019, accounting for about one-third of all deaths globally.1 The primary cause of CVD-related death and morbidity is ischaemic ...

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Cardiac complications constitute a common cause of morbidity and mortality in the perioperative period, contributing to over a third of perioperative deaths.1 More than 230 million major surgeries are performed annually worldwide, with older patients representing an increasing proportion of the ...

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A significant proportion of patients with atrial fibrillation (AF) who have a high stroke risk are currently being treated with oral anticoagulation (OAC), including direct oral anticoagulants (DOACs) and vitamin K inhibitors (VKAs).1 It is well known that the increased ...

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Despite improved treatment of atherosclerotic cardiovascular disease, coronary artery disease (CAD) remains the leading cause of death and disability worldwide.1 Treatment of traditional risk factors, mainly low-density lipoprotein (LDL) cholesterol, is the foundation of atherosclerotic risk reduction. However, a considerable ...

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A common complication of endovascular repair of an abdominal aortic aneurysm (EVAR) is the persistence of blood flow outside the lumen of the endoprosthesis, known as an endoleak. Endoleaks are a potentially lethal complication and occur following up to 25% of ...

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There are several beneficial effects of statins on the progression of atherosclerosis, and there have been significant advancements in pharmacotherapies for atherosclerotic cardiovascular disease (ASCVD). However, substantial residual cardiovascular (CV) risk remains, and there is an unmet need to reduce ...

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Jean-Marc Foult, Shruthi Pranesh, Matthew Budoff

More than half of acute coronary syndromes (ACS) occur in subjects with no significant coronary stenosis.1 In view of the number of patients dying each year from a heart attack, the question of identifying these patients is of primary importance. ...

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Bicuspid aortic valve (BAV) represents the most common congenital cardiac anomaly, with a prevalence ranging between 1% and 2% in the general population.1 BAV is known to be associated with dilation and dissection of the ascending aorta, and the significantly higher shear ...

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Anomalous coronary arteries originating from the opposite sinus of Valsalva (ACAOS) is one of the most clinically relevant abnormalities among the wide spectrum of coronary artery anomalies.1 Sudden cardiac death has been related to myocardial bridges, ectopic origin of the ...

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Cardiovascular disease (CVD) represents the prevailing cause of death in the United States.1 Cancer, accidents and other prevalent causes of death, have a multitude of pathophysiologic and mechanistic underpinnings leading to mortality. Meanwhile, the majority of CVD is primarily attributable ...

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Optimal medical therapy (OMT) is the cornerstone of management in patients with coronary atheroma, given the substantial evidence that it can delay disease progression and damp down both chronic and acute vascular inflammation, thereby leading to a reduction in cardiovascular ...

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Individuals with aortic stenosis frequently have coronary artery disease (CAD).1 Both conditions share a common pathophysiology involving low‐density lipoprotein-mediated inflammatory response, resulting in an accelerated atherosclerotic process.2 They also share similar risk factors, such as age, smoking, hypertension, diabetes ...

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- Insight into the CRISP-CT study, which was presented at the European Society of Cardiology Congress, Munich, Germany, 25–29 August, 2018   Atherosclerosis is a common disease in which plaques, formed from fatty deposits, develop in the inner layers of arteries. Over time, ...

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