77/Procedural safety and acute effectiveness of pulsed field ablation for treatment of atrial fibrillation – a report on the first series of cases in the UK
LH Hong (Presenting Author) – University of Cambridge, Cambridge; J Mesquita – Royal Papworth Hospital, Cambridge; J Eldridge – Royal Papworth Hospital, Cambridge; DA Begley – Royal Papworth Hospital, Cambridge; PM Heck – Royal Papworth Hospital, Cambridge; CA Martin – Royal Papworth Hospital, Cambridge
Introduction: Pulsed field ablation (PFA) is a novel, non-thermal, atrial fibrillation (AF) ablation technique, in which delivery of millisecond electrical pulses generates pores in cell membranes, leading to its disruption (electroporation). PFA has demonstrated high selectivity for cardiomyocytes, thus reducing the risk of collateral extracardiac tissue damage often associated with thermal ablation methods. Both preclinical […]