Epicardial adipose tissue (EAT) is a fat collection directly adjacent to the myocardium and coronary vasculature, lacking any separation and sharing the same circulation.1,2 This anatomy enables direct signalling between EAT and the surrounding tissue, positioning EAT as a central ...

Highlights The autonomic nervous system plays a critical role in the aetiopathogenesis of atrial fibrillation (AF). Neuromodulation of the autonomic nervous system has been a topic of increased interest in the management of AF. Ablation of ganglionated plexi, ethanol ablation ...

Diabetes mellitus (DM) is strongly associated with severe macro- and micro-vascular complications; it is also proven to be a strong independent risk factor for developing heart failure (HF).1 In fact, the prevalence of DM is reported to be as high ...

Heart failure (HF) is an increasingly prevalent clinical syndrome resulting from a variety of disease processes impeding the heart’s ability to effectively circulate blood. With advances in care and a steadily growing and aging population, HF management is becoming ...

The purpose of this report is to describe an unusual case of arrhythmogenic cardiomyopathy, involving the left ventricle (LV), with an atypical standard electrocardiogram (ECG) pattern. Sustained ventricular arrhythmias in a middle-aged subject are usually related to ischemic heart disease. ...

Introduction: Increased volume of epicardial adipose tissue (EAT) is now well established as an independent risk factor for all forms of atrial fibrillation (AF). EAT acts as a local compartment of immune cells and mediators that can infiltrate the myocardium ...

Introduction: Obesity confers higher risks of cardiac arrhythmias and sudden cardiac death. Given that early bariatric surgery reverses and prevents some metabolic complications of obesity, the same may also be true for the risk of cardiac arrhythmias. However, the evidence ...

Background: Obesity has been strongly associated with atrial and ventricular arrhythmias. This effect is, in part, mediated by epicardial adipose tissue (EAT), which has previously shown to have a pro-arrhythmic secretome. Therefore, we sought to confirm any paracrine effects of ...

Introduction: Obesity which is characterised by excess adipose tissue (AT) has been associated with increased risk of arrhythmia. AT functions as an endocrine organ and secretes adipokines which may induce a proarrhythmic substrate. Specifically, epicardial AT (EAT) has been associated ...