Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary ...

  Atrial fibrillation (AF) is one of the most frequent arrhythmias worldwide, and, despite progress in the management of patients with AF, remains one of the major causes of stroke, heart failure, sudden death, and cardiovascular morbidity.1 The incidence and ...

With the introduction of invasive and noninvasive phase mapping in humans, visualisation of rotor activity during atrial fibrillation has emerged as a new concept.1–3 However, phase maps rendered during human atrial fibrillation using noninvasive information from body-surface electrocardiograms (ECGs) versus ...

Background: Atrial fibrillation (AF) is characterised by an irregularly irregular ventricular rhythm. However, an understanding of the mechanisms by which the regularity of ventricular response is influenced by AF dynamics is still lacking. In AF, atrial electrical activity can have ...

Introduction: Characterising patient-specific atrial fibrillation (AF) phenotype may lead to individualised approaches and improve ablation outcomes. Our novel mapping approach based on signal recurrence plots has not previously been applied to whole chamber, bi-atrial recording of AF. Methods: Simultaneous bi-atrial 30...

Background: Applying conventional approaches of ‘window of interest’ setting and local activation time (LAT) assignment to map atrial fibrillation (AF) is difficult. We overcame this problem using an algorithm to time-shift for best match of adjacent electrograms, using these relative ...

Background: We evaluated the effect of adenosine upon mechanisms sustaining persistent AF through analysis of contact electrograms and ECGI mapping. Methods: Persistent AF patients undergoing catheter ablation were included. ECGI maps and cycle length (CL) measurements were recorded in the ...

Background: Localised drivers in the form of intermittent focal and rotational activations have been proposed as mechanisms sustaining persistent AF. The possibility of a relationship between these phenomena has not been explored and any interaction with structural remodelling remains unclear. ...

Background: Recent studies have suggested pulmonary vein isolation (PVI) alone is as effective as strategies incorporating additional substrate modification in patients with persistent atrial fibrillation (AF). It remains unclear if PVI impacts upon the mechanisms that sustain or remove triggers ...