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Pressure measurement of hypertension in elderly woman sitting on couch, young woman nurse or caregiver care checking, measuring heart, blood by using sphygmomanometer monitor
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Hypertension affects over 1.4 billion adults worldwide and remains the leading modifiable risk factor for global cardiovascular (CV) morbidity and mortality. It is responsible for an estimated 10.8 million deaths annually and contributes significantly to the global burden of ischaemic heart disease, ...

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Gagan Priya, Shibba Takkar Chhabra, Sanjay Kalra

Several closely regulated ion channels are involved in the various phases of the myocardial action potential (phases 0–4) (Figure 1).1 In the absence of neuroendocrine and other regulatory signals, the pacing rate of the sinoatrial node is 100 beats per minute (bpm). However, ...

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