124 Results Found for “meta-analysis”
At ESC Congress 2026, Dr Rami Abu Fanne (Hillel Yaffe Medical Center and Hadassah Medical Center, The Hebrew University of Jerusalem) presented an analysis exploring whether baseline vitamin D levels were associated with metabolic response to semaglutide in people with type 2 diabetes. The study included 5,300 adults and found that higher baseline vitamin D levels were associated with greater improvements in glycemic control and BMI after 12 months of treatment, although no association was observed with lipid outcomes. Dr Abu Fanne spoke to touchCARDIO about the findings and the questions they raise for future research.
Arrowhead Pharmaceuticals, Inc. (Pasadena, CA) has reported topline results from two phase III trials evaluating plozasiran in adults with severe hypertriglyceridemia (sHTG), according to a recent press release.1 Plozasiran, an siRNA therapy directed against apolipoprotein C-III (APOC3) messenger RNA, is already approved as Redemplo for adults with familial chylomicronemia syndrome but remains investigational for the broader sHTG population.
Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary ...
Sudden cardiac arrest (SCA) in young adults (typically defined as individuals younger than 40 years) has emerged as an important yet under-recognized public health concern. Recent estimates suggest an incidence of approximately 1–4 cases per 100,000 person-years, underscoring the clinical and epidemiological relevance ...
At EHRA 2026, Pierre Jais presented results from the BEAT-PERS AF trial suggesting pulsed field ablation may offer a safer, effective alternative to radiofrequency ablation in persistent AF, prompting renewed focus on optimizing ablation strategies for this high-risk group.
At EHRA 2026, Ben Petrazzini discussed new research that shows AI can improve identification of sudden cardiac death in electronic health records, enabling more accurate large-scale studies and advancing prevention strategies.
New data to be presented at ACC 2026 suggest that shingles vaccination is associated with a reduced risk of major cardiovascular events, including myocardial infarction and stroke. In a large observational analysis, vaccinated individuals showed lower event rates within 12 months of follow-up. While the findings are subject to study limitations, they add to growing evidence linking infection prevention with cardiovascular risk reduction.
Hypertension affects over 1.4 billion adults worldwide and remains the leading modifiable risk factor for global cardiovascular (CV) morbidity and mortality. It is responsible for an estimated 10.8 million deaths annually and contributes significantly to the global burden of ischaemic heart disease, ...
A first-of-its-kind CAR Treg therapy has shown plaque-reducing effects in a preclinical model of atherosclerosis, signalling a potential shift toward targeted immunomodulation in cardiovascular disease. Could OxLDL-directed Tregs become the next major advance in cardio-immunotherapy?
Cardiovascular medicine continues to advance at a remarkable pace, driven by innovation, interdisciplinary collaboration and an ever-deepening understanding of disease mechanisms. As patient populations age and chronic conditions become increasingly complex, the field stands at the intersection of precision therapy, ...
Heart failure (HF) is a complex and progressive clinical syndrome that significantly impacts morbidity, mortality and quality of life (QoL).1 On a global scale, HF has become an escalating public health concern, affecting more than 64 million individuals in 2017, and this ...
Heart failure (HF) is a global health burden, with a 2019 prevalence of 711.90 per 100,000 population, totalling 56.19 million cases and 5.05 million years lived with disability, despite only modest declines since 1990.1 Recent years have shown an uptick in prevalence, driven by ageing populations ...
Epicardial adipose tissue (EAT) is a fat collection directly adjacent to the myocardium and coronary vasculature, lacking any separation and sharing the same circulation.1,2 This anatomy enables direct signalling between EAT and the surrounding tissue, positioning EAT as a central ...
Cardiovascular disease (CVD) is one of the major causes of morbidity and mortality throughout the world.1,2 While traditional risk factors are managed intensively, many individuals continue to have considerable residual risk, and emerging factors such as inflammatory mediators are being ...
The 2025 American Heart Association (AHA) Scientific Sessions (7–10 November; New Orleans, LA, USA) offered a comprehensive overview of the evolving landscape of cardiovascular medicine. This year’s research showcased pivotal trials spanning indications, including hypercholesterolemia, hypertrophic cardiomyopathy, amyloidosis, severe hypertriglyceridaemia, hypertension, ...
ObesityWeek® 2025 highlighted obesity as a chronic, multi-system disease that links cardiovascular, renal, and metabolic health. New data from clinical trials showcased therapies improving weight, blood pressure, and inflammation, signalling a shift toward integrated care where obesity management becomes central to cardiovascular risk reduction.
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