{"id":16109,"date":"2022-05-03T14:50:24","date_gmt":"2022-05-03T13:50:24","guid":{"rendered":"https:\/\/touchcardio.com\/?post_type=media_gallery&p=16109"},"modified":"2022-05-30T14:55:00","modified_gmt":"2022-05-30T13:55:00","slug":"brian-bergmark-acc-2022-translate-timi-70-effect-of-vupanorsen-on-non-high-density-lipoprotein-cholesterol-levels-in-statin-treated-patients-with-elevated-cholesterol","status":"publish","type":"media_gallery","link":"https:\/\/touchcardio.com\/atherosclerosis\/conference-hub\/brian-bergmark-acc-2022-translate-timi-70-effect-of-vupanorsen-on-non-high-density-lipoprotein-cholesterol-levels-in-statin-treated-patients-with-elevated-cholesterol\/","title":{"rendered":"Brian Bergmark, ACC 2022: TRANSLATE-TIMI 70: Effect of vupanorsen on non-high-density lipoprotein cholesterol levels in statin-treated patients with elevated cholesterol"},"content":{"rendered":"

The TRANSLATE-TIMI 70 trial looks at the effect of vupanorsen on non-high-density lipoprotein cholesterol levels in statin-treated patients with elevated cholesterol. touchCARDIO spoke with Dr Brian Bergmark<\/strong> (Brigham and Women’s Hospital, Boston, MA) about the use of vupanorsen and the safety and efficacy of the TRANSLATE-TIMI 7 trial.<\/p>\n

Questions:<\/strong><\/p>\n

    \n
  1. What is vupanorsen and what is the rationale for its use as a lipid-lowering agent? (00:19)<\/li>\n
  2. What are the aims, design, and eligibility criteria of the TRANSLATE-TIMI 7 clinical trial? (01:34)<\/li>\n
  3. What were the efficacy and safety findings of the study? (03:02)<\/li>\n
  4. What will be the next step in the clinical development of vupanorsen in this indication? (04:25)<\/li>\n
  5. What are the other potential indications of vupanorsen? (06:15)<\/li>\n<\/ol>\n

    Disclosures:<\/strong> Brian Bergmark discloses grant\/research support from Pfizer, AstraZeneca and Ionis.<\/p>\n

    Support:<\/strong> Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.<\/p>\n

    Filmed in coverage of the American College of Cardiology Annual Meeting 2022<\/p>\n","protected":false},"excerpt":{"rendered":"

    The TRANSLATE-TIMI 70 trial looks at the effect of vupanorsen on non-high-density lipoprotein cholesterol levels in statin-treated patients with elevated cholesterol. touchCARDIO spoke with Dr Brian Bergmark (Brigham and Women’s Hospital, Boston, MA) about the use of vupanorsen and the safety and efficacy of the TRANSLATE-TIMI 7 trial. Questions: What is vupanorsen and what is […]<\/p>\n","protected":false},"featured_media":16110,"template":"","class_list":["post-16109","media_gallery","type-media_gallery","status-publish","has-post-thumbnail","hentry","vocabulary_1-atherosclerosis","video_categories-acc-highlights"],"acf":[],"_links":{"self":[{"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/media_gallery\/16109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/media_gallery"}],"about":[{"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/types\/media_gallery"}],"version-history":[{"count":4,"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/media_gallery\/16109\/revisions"}],"predecessor-version":[{"id":16685,"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/media_gallery\/16109\/revisions\/16685"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/media\/16110"}],"wp:attachment":[{"href":"https:\/\/touchcardio.com\/wp-json\/wp\/v2\/media?parent=16109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}