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EUROPEAN JOURNAL OF ARRHYTHMIA & ELECTROPHYSIOLOGY – VOLUME 8 SUPPLEMENT 1 – 2022

The official abstracts from the Heart Rhythm Congress (HRC) 2022

Young Investigators Competition
Oral Abstracts 1 – Allied & Service Development
Oral Abstracts 1 – Arrhythmia Clinical
Oral Abstracts 2 – High-scoring Abstracts
Oral Abstracts 2 – Arrhythmia Mechanisms/In Silico Tools
Oral Abstracts 3 – Devices
Oral Abstracts 3 – Mapping & Ablation
Moderated Posters 1
Moderated Posters 2
Paediatric
Index of Presenting Authors

Young Investigators Competition

Arrhythmia
Arrhythmia
1/Impact of left ventricular scar burden on acute response to conduction system pacing
N Ali (Presenting Author) - National Heart and Lung Institute, Imperial College London, London; AA Miyazawa - National Heart and Lung Institute, Imperial College London, London; AD Arnold - National Heart and Lung Institute, Imperial College London, London; P Kanagratnam - National Heart and Lung Institute, Imperial College London, London; NS Peters - National Heart and Lung Institute, Imperial College London, London; N Qureshi - National Heart and Lung Institute, Imperial College London, London; B Lim - National Heart and Lung Institute, Imperial College London, London; F Ng - National Heart and Lung Institute, Imperial College London, London; N Linton - National Heart and Lung Institute, Imperial College London, London; D Lefroy - National Heart and Lung Institute, Imperial College London, London; A Muthumala - St Bartholomews Hospital and North Middlesex University Hospital, London; MA Tanner - St Richards Hospital, University Hospitals Sussex NHS Foundation Trust, London; D Keene - National Heart and Lung Institute, Imperial College London, London; GD Cole - National Heart and Lung Institute, Imperial College London, London; D Francis - National Heart and Lung Institute, Imperial College London, London; ZA Whinnett - Imperial College London, London

Introduction: Conduction system pacing is a novel way for delivering cardiac resynchronisation therapy (CRT). This may deliver more effective ventricular resynchronisation than the gold standard, biventricular pacing (BVP). In BVP scar burden is known to impact response but whether this is true for conduction system pacing is unknown. Methods: Patients with standard CRT indications were […]

Basic Scientist

Oral Abstracts 1 - Allied and Service Development

Oral Abstracts 1 – Arrhythmia Clinical

Oral Abstracts 2 – High-scoring Abstracts

Arrhythmia
Arrhythmia
19/The electrophysiologic substrate of Brugada syndrome patients can be revealed by electrocardiographic imaging
JJ Chow (Presenting Author) – Imperial College Healthcare NHS Trust, London; K Leong – Imperial College Healthcare NHS Trust, London; M Shun-Shin – Imperial College Healthcare NHS Trust, London; OP Guttmann – Barts Health NHS Trust, London; SA Mohiddin – Barts Health NHS Trust, London; P Lambiase – Barts Health NHS Trust, London; PM Elliott – Barts Health NHS Trust, London; JOM Ormerod – Oxford University Hospitals NHS Trust, Oxford; M Koa-Wing – Imperial College Healthcare NHS Trust, London; DC Lefroy – Imperial College Healthcare NHS Trust, London; P Boon Lim – Imperial College Healthcare NHS Trust, London; NWF Linton – Imperial College Healthcare NHS Trust, London; FS Ng – Imperial College Healthcare NHS Trust, London; NA Qureshi – Imperial College Healthcare NHS Trust, London; ZI Whinnett – Imperial College Healthcare NHS Trust, London; NS Peters – Imperial College Healthcare NHS Trust, London; DP Francis – Imperial College Healthcare NHS Trust, London; AM Varnava – Imperial College Healthcare NHS Trust, London; P Kanagaratnam – Imperial College Healthcare NHS Trust, London

Introduction: Brugada syndrome (BrS) is an important cause of sudden cardiac death but diagnosis can be challenging. Body surface ECG changes in BrS are dynamic, and elicitation by sodium channel blockade carries a risk of death. The epicardial substrate of the overt Type 1 BrS ECG is known but not always spontaneously present in cardiac […]

Atrial Fibrillation
Atrial Fibrillation
20/Real-world results of oesophageal protection during left atrial ablation
L Leung (Presenting Author) – St George’s University Hospitals NHS Foundation Trust, London; A Bajpai – St George’s University Hospitals NHS Foundation Trust, London; A Li – St George’s University Hospitals NHS Foundation Trust, London; M Norman – St George’s University Hospitals NHS Foundation Trust, London; R Kaba – St George’s University Hospitals NHS Foundation Trust, London; G Dhillon – St George’s University Hospitals NHS Foundation Trust, London; Z Akhtar – St George’s University Hospitals NHS Foundation Trust, London; M Sohal – St George’s University Hospitals NHS Foundation Trust, London; N Al-Subaie – St George’s University Hospitals NHS Foundation Trust, London; J Louis-Auguste – St George’s University Hospitals NHS Foundation Trust, London; J Hayat – St George’s University Hospitals NHS Foundation Trust, London; Z Zuberi – St George’s University Hospitals NHS Foundation Trust, London; MM Gallagher – St George’s University Hospitals NHS Foundation Trust, London

Background: Randomised trial evidence suggests that active control of local temperature can prevent thermal injury to the oesophagus; alternative methods of protection have been proposed, including the measurement of luminal temperature, and mechanical deviation away from the source of energy. Specific devices are available for each role. Objective: To use multiple sources of real-world evidence […]

Heart Failure
Heart Failure
24/The effect of His bundle pacing vs conventional biventricular pacing on repolarisation in patient’s with heart failure and reduced ejection fraction and left bundle branch block?
JW Samways (Presenting Author) – Imperial College Healthcare NHS Trust, London; AD Arnold – Imperial College Healthcare NHS Trust, London; MJ Shun-Shin – Imperial College Healthcare NHS Trust, London; N Ali – Imperial College Healthcare NHS Trust, London; T Cheng – Imperial College London, London; JP Howard – Imperial College Healthcare NHS Trust, London; D Keene – Imperial College Healthcare NHS Trust, London; FS Ng – Imperial College Healthcare NHS Trust, London; M Tanner – Imperial College Healthcare NHS Trust, London; PB Lim – Imperial College Healthcare NHS Trust, London; NW F Linton – Imperial College Healthcare NHS Trust, London; NS Peters – Imperial College Healthcare NHS Trust, London; P Kanagaratnam – Imperial College Healthcare NHS Trust, London; DP Francis – Imperial College Healthcare NHS Trust, London; ZI Whinnett – Imperial College Healthcare NHS Trust, London

Introduction: Left bundle branch block (LBBB) is associated with an increased risk of ventricular arrhythmia. Biventricular pacing (BVP) improves symptoms, systolic left ventricular function and mortality in heart failure with LBBB, but can be pro-arrhythmic. His bundle pacing (HBP) can overcome LBBB to produce more synchronous ventricular activation than BVP, but it is not known […]

Oral Abstracts 2 – Arrhythmia Mechanisms/In Silico Tools

Atrial Fibrillation
Atrial Fibrillation
25/Creating patient-specific atrial fibrillation models from imaging and electroanatomic mapping data
GR Raffaele (Presenting Author) – Faculty of Life Sciences and Medicine, King’s College London, London; CHR Roney – School of Biomedical Engineering and Imaging Sciences, King’s College London; School of Engineering and Materials Science, Queen Mary University of London, London; IK Kotadia – School of Biomedical Engineering and Imaging Sciences, King’s College London, London; JAS-L Solis-Lemus – School of Biomedical Engineering and Imaging Sciences, King’s College London, London; IS Sim – School of Biomedical Engineering and Imaging Sciences, King’s College London, London; JW Whitaker – School of Biomedical Engineering and Imaging Sciences, King’s College London; The Department of Internal Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Boston; OR Razeghi – School of Biomedical Engineering and Imaging Sciences, King’s College London, London; MO O’Neill – School of Biomedical Engineering and Imaging Sciences, King’s College London, London; SEW Williams – School of Biomedical Engineering and Imaging Sciences, King’s College London, London; Centre for Cardiovascular Science, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh; SMN Narayan – Department of Medicine and Cardiovascular Institute, Stanford University, Palo Alto; SAN Niederer – School of Biomedical Engineering and Imaging Sciences, King’s College London, London

Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting over 1.4 million people in the UK alone, and is associated with an increased risk of cardiovascular diseases, stroke and death. AF is often treated by catheter ablation therapy, which aims to isolate regions of the atrial tissue that are critical for driving the […]

Arrhythmia
Arrhythmia
27/Artificial intelligence-enabled electrocardiogram to distinguish cavotricuspid isthmus dependence from other atrial tachycardia mechanisms
A Sau (Presenting Author) – Imperial College London, London; S Ibrahim – Imperial College London, London; A Ahmed – Imperial College London, London; B Handa – Imperial College London, London; DB Kramer – Beth Israel Deaconess Medical Center, Boston; JW Waks – Beth Israel Deaconess Medical Center, Boston; AD Arnold – Imperial College London, London; JP Howard – Imperial College London, London; N Qureshi – Imperial College London, London; M Koa-Wing – Imperial College London, London; D Keene – Imperial College London, London; L Malcolme-Lawes – Imperial College London, London; DC Lefroy – Imperial College London, London; NWF Linton – Imperial College London, London; PB Lim – Imperial College London, London; A Varnava – Imperial College London, London; ZI Whinnett – Imperial College London, London; P Kanagaratnam – Imperial College London, London; D Mandic – Imperial College London, London; NS Peters – Imperial College London, London; FS Ng – Imperial College London, London

Background: Accurately determining atrial arrhythmia mechanisms from a 12-lead ECG can be challenging. Given the high success rate of cavotricuspid isthmus (CTI) ablation, accurate identification of CTI-dependent typical atrial flutter (AFL) is important for treatment decisions and procedure planning. Machine learning, with convolutional neural networks (CNNs) in particular, has been used to classify arrhythmias using […]

Arrhythmia
Arrhythmia
28/UHF-ECG detected QRS fractionation predicts arrhythmic risk in patients with hereditary arrhythmic conditions
K Saleh (Presenting Author) – National Heart and Lung Institute, Imperial College London, London; A Varnava – National Heart and Lung Institute, Imperial College London, London; M Shun-Shin – National Heart and Lung Institute, Imperial College London, London; N Ali – National Heart and Lung Institute, Imperial College London, London; J Mohal – National Heart and Lung Institute, Imperial College London, London; K Chiew – National Heart and Lung Institute, Imperial College London, London; M Hanif – National Heart and Lung Institute, Imperial College London, London; A Merzah – National Heart and Lung Institute, Imperial College London, London; J Howard – National Heart and Lung Institute, Imperial College London, London; P Jurak – Institute of Scientific Instruments of the Czech Academy of Sciences, Brno; P Leinveber – International Clinical Research Center, St. Anne’s University Hospital, Brno; P Kanagaratnam – National Heart and Lung Institute, Imperial College London, London; D Francis – National Heart and Lung Institute, Imperial College London, London; Z Whinnett – National Heart and Lung Institute, Imperial College London, London; A Arnold – National Heart and Lung Institute, Imperial College London, London

Introduction: Fragmentation of the QRS complex is a feature of arrhythmogenic conditions including primary arrhythmia syndromes, ischaemic and non-ischaemic cardiomyopathy and in the presence of myocardial scar. While gross fragmentation can be observed on 12-lead ECG, more subtle abnormalities may be missed. Ultra-high-frequency ECG (UHF-ECG) is an ECG-based technique that measures electrical activation signals in […]

Arrhythmia
Arrhythmia
29/The electrophysiological substrate of HCM and propensity to ventricular fibrillation as measured by ECG imaging
JJ Chow (Presenting Author) – Imperial College Healthcare NHS Trust, London; K Leong – Imperial College Healthcare NHS Trust, London; M Shun-Shin – Imperial College Healthcare NHS Trust, London; OP Guttmann – Barts Health NHS Trust, London; SA Mohiddin – Barts Health NHS Trust, London; P Lambiase – Barts Health NHS Trust, London; PM Elliott – Barts Health NHS Trust, London; JOM Ormerod – Oxford University Hospitals NHS Trust, Oxford; M Koa-Wing – Imperial College Healthcare NHS Trust, London; DC Lefroy – Imperial College Healthcare NHS Trust, London; P Boon Lim – Imperial College Healthcare NHS Trust, London; NWF Linton – Imperial College Healthcare NHS Trust, London; FS Ng – Imperial College Healthcare NHS Trust, London; NA Qureshi – Imperial College Healthcare NHS Trust, London; ZI Whinnett – Imperial College Healthcare NHS Trust, London; NS Peters – Imperial College Healthcare NHS Trust, London; DP Francis – Imperial College Healthcare NHS Trust, London; AM Varnava – Imperial College Healthcare NHS Trust, London; P Kanagaratnam – Imperial College Healthcare NHS Trust, London

Patients with hypertrophic cardiomyopathy (HCM) are at risk of lethal ventricular arrhythmia. The electrical substrate for this has not been well elucidated. Furthermore, despite extensive knowledge of the structural differences in HCM vs the normal heart, the effects of electrophysiology are not known. Methods: HCM patients surviving ventricular fibrillation or haemodynamically unstable ventricular tachycardia (HCM […]

Oral Abstracts 3 – Devices

Oral Abstracts 3 – Mapping and Ablation

Atrial Fibrillation
Atrial Fibrillation
37/Patient experience of very high-power short-duration radiofrequency ablation for atrial fibrillation under mild conscious sedation
GS Chu (Presenting Author) – Lancashire Cardiac Centre, Blackpool; P Calvert – Liverpool Heart and Chest Hospital, Liverpool; B Sidhu – University of Leicester, Leicester; A Mavilakandy – University of Leicester, Leicester; A Kotb – University of Leicester, Leicester; L Tovmassian – Liverpool Heart and Chest Hospital, Liverpool; N Kozhuharov – Liverpool Heart and Chest Hospital, Liverpool; C Biermé – Liverpool Heart and Chest Hospital, Liverpool; N Denham – Liverpool Heart and Chest Hospital, Liverpool; C Pius – Liverpool Heart and Chest Hospital, Liverpool; J O’Brien – Liverpool Heart and Chest Hospital, Liverpool; WY Ding – Liverpool Heart and Chest Hospital, Liverpool; V Luther – Liverpool Heart and Chest Hospital, Liverpool; R Snowdon – Liverpool Heart and Chest Hospital, Liverpool; GA Ng – University of Leicester, Leicester; D Gupta – Liverpool Heart and Chest Hospital, Liverpool

Background: Conventional radiofrequency (RF) ablation for atrial fibrillation (AF) can cause significant patient discomfort even under mild conscious sedation (mCS), contributing to the predominant use of cryoablation (Cryo) for pulmonary vein isolation (PVI). We hypothesized that by reducing energy delivery times, a very high-power short-duration (vHPSD) RF protocol could offer a patient experience comparable to […]

Moderated Posters 1

Moderated Posters 2

Posters 1

Arrhythmia
Developed by Touch
Arrhythmia
86/The role of atrioventricular delay shortening and ventricular resynchronisation in achieving the haemodynamic benefit seen in biventricular pacing
A Naraen (Presenting Author) – St Helen’s Knowlsely Teaching Hospitals Trust, Liverpool; AD Arnold – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; MJ Shun-Shin – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; N Ali – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; D Keene – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; JP Howard – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; J Chow – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; IJ Wright – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; FS Ng – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; NA Qureshi – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; M Koa-Wing – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; DC Lefroy – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; NWF Linton – Department of Bioengineering, Imperial College London, Hammersmith Hospital, London; PB Lim – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; NS Peters – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; A Muthumala – Cardiology Department, North Middlesex University Hospital NHS Trust; Cardiology Department, St Bartholomew’s Hospital, Barts Health NHS Trust, London; M Tanner – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; KA Ellenbogen – Division of Cardiac Electrophysiology, Virginia Commonwealth University, Richmond; P Kanagaratnam – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; DP Francis – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London; ZI Whinnett – National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London

Background: It is assumed that resynchronisation of the ventricles in patients with heart failure and left bundle branch block (LBBB) delivers the most benefit in biventricular pacing (BVP). Because cardiac resynchronisation therapy (CRT) with BVP both shortens atrioventricular delay and reduces ventricular dyssynchrony, it is difficult to isolate their individual impact. Objectives: In this invasive […]

Posters 2

Interventional Cardiology
Interventional Cardiology
98/Cardiac implantable electronic device infections: multicentre validation of a novel risk score and its cost–utility implications for antimicrobial envelope use
E Maclean (Presenting Author) – St Bartholomew’s Hospital, London; K Mahtani – St. Bartholomew’s Hospital, London; S Honarbakhsh – St. Bartholomew’s Hospital, London; C Butcher – St. Bartholomew’s Hospital, London; N Ahluwalia – St. Bartholomew’s Hospital, London; ASC Dennis – St. Bartholomew’s Hospital, London; P Waddingham – St. Bartholomew’s Hospital, London; A Creta – St. Bartholomew’s Hospital, London; M Finlay – St. Bartholomew’s Hospital, London; M Elliott – St. Thomas’ Hospital, London; V Mehta – St. Thomas’ Hospital, London; N Wijesuriya – St. Thomas’ Hospital, London; O Shaikh – Royal Papworth Hospital, Cambridge; M Zaw – Royal Papworth Hospital, Cambridge; CN Ranmuthu – Royal Papworth Hospital, Cambridge; CR Ranmuthu – Royal Papworth Hospital, Cambridge; RJ Schilling – St. Bartholomew’s Hospital, London; PD Lambiase – St. Bartholomew’s Hospital, London; MJ Earley – St. Bartholomew’s Hospital, London; P Moore – St. Bartholomew’s Hospital, London; A Muthumala – St. Bartholomew’s Hospital, London; S Sporton – St. Bartholomew’s Hospital, London; RJ Hunter – St. Bartholomew’s Hospital, London; C Rinaldi – St. Thomas’ Hospital, London; JM Behar – St. Thomas’ Hospital, London; C Martin – Royal Papworth Hospital, Cambridge; C Monkhouse – St. Bartholomew’s Hospital, London; A Chow – St. Bartholomew’s Hospital, London

Introduction: Antimicrobial envelopes reduce the incidence of cardiac implantable electronic device (CIED) infections; however, patient selection strategies are poorly defined and cost–utility data are limited. Methods: In a preliminary internal analysis, we examined the factors associated with infection for all transvenous CIED implants, generator changes and non-infected lead interventions at a single tertiary centre from […]

Atrial Fibrillation
Atrial Fibrillation
113/Left atrial appendage occlusion for atrial fibrillation and bleeding diathesis
BS Kailey (Presenting Author) – Imperial College London, London; M Koa-Wing – Imperial College Healthcare NHS Trust, London; N Sutaria – Imperial College Healthcare NHS Trust, London; T Mott – Abbott Healthcare, London; A Sohaib – Barts Healthcare NHS Trust, London; N Qureshi – Imperial College Healthcare NHS Trust, London; C Wadsworth – Imperial College Healthcare NHS Trust, London; S Jamil – Imperial College Healthcare NHS Trust, London; L D’Anna – Imperial College Healthcare NHS Trust, London; C Shi – Imperial College Healthcare NHS Trust, London; P Padam – Imperial College Healthcare NHS Trust, London; J Howard – Imperial College Healthcare NHS Trust, London; S Levy – Imperial College Healthcare NHS Trust, London; B Porter – Imperial College Healthcare NHS Trust, London; Z Whinnett – Imperial College Healthcare NHS Trust, London; N Linton – Imperial College Healthcare NHS Trust, London; B Lim – Imperial College Healthcare NHS Trust, London; N Peters – Imperial College Healthcare NHS Trust, London; FS Ng – Imperial College Healthcare NHS Trust, London; D Keene – Imperial College Healthcare NHS Trust, London; L Malcolme-Lawes – Imperial College Healthcare NHS Trust, London; D Lefroy – Imperial College Healthcare NHS Trust, London; G Cole – Imperial College Healthcare NHS Trust, London; P Asaria – Imperial College Healthcare NHS Trust, London; B Ariff – Imperial College Healthcare NHS Trust, London; D Gopalan – Imperial College Healthcare NHS Trust, London; A Varnava – Imperial College Healthcare NHS Trust, London; P Pabari – Imperial College Healthcare NHS Trust, London; B Rana – Imperial College Healthcare NHS Trust, London; P Kanagaratnam – Imperial College Healthcare NHS Trust, London

Introduction: Patients with atrial fibrillation (AF) and likelihood of bleeding can undergo left atrial appendage occlusion (LAAO) as an alternative method of stroke prophylaxis. A short course of anti-thrombotic drugs is used post-procedure to offset the risk of device-related thrombus, but evidence for this practice is limited. Methods: Patients with AF and high risk for […]

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