Hypertension (HTN) is one of the largest contributors to cardiovascular (CV) morbidity and mortality in the USA and is estimated to affect 47% of the adult population or approximately 122 million adults older than 20 years of age.1 Recent estimates suggest that over 40% of these patients continue to have uncontrolled blood pressure (BP) and that […]

Over the past two decades, the field of transcatheter aortic valve replacement (TAVR) has experienced remarkable advancement. Initially approved for patients with high and prohibitive surgical risk, TAVR has progressively extended its indications to all patients, regardless of surgical risk. Beyond the expansion of indications, substantial efforts have been dedicated to refining and optimizing both […]

Catheter ablation (CA) is an invasive adjunctive therapeutic option for atrial and ventricular arrhythmias, in uncontrolled cases, following optimal medical therapy.1,2 The validation of 3D mapping and its implementation into clinical usage has been a remarkable achievement in the field of complex ablation of scar-related ventricular tachycardia (VT) in the early 2000s.3 In the setting of atrial […]

Cardiovascular disease (CVD) continues to be the leading cause of death on a global scale. Nearly 18 million people died from CVD in 2019, accounting for about one-third of all deaths globally.1 The primary cause of CVD-related death and morbidity is ischaemic heart disease (IHD). Since 1990, the total number of disability adjusted life years (DALYs) […]

Clinically relevant tricuspid regurgitation (TR) is a common disorder, affecting approximately 4% of people 75 years of age or older.1 If left untreated, severe TR results in volume overload and right ventricular remodelling. This eventually leads to symptomatic right-sided heart failure, along with increased morbidity and mortality. This disease is highly undertreated due to high complication […]

Welcome to the latest issue of the European Journal of Arrhythmia & Electrophysiology, the official journal of the Arrhythmia Alliance. We are honoured to present a series of compelling articles that reflect cutting-edge developments and diverse perspectives in this ever-evolving field. Richard Ang opens the edition with the first in a series of expert interviews […]

Vasovagal syncope (VVS), the most common cause of fainting, is predominantly caused by an overactive vagal tone, leading to asystole, sinus bradycardia, or atrioventricular block.1 This condition, a form of neurocardiogenic syncope, is characterized by a pronounced vagal reflex that causes reflex-induced hypotension and bradycardia. Traditional management strategies, including increased salt and water intake, physical counterpressure […]

The landscape of managing atrial fibrillation (AF), the most common cardiac arrhythmia and leading cause of stroke, has undergone a period of change following the development of various treatment modalities and risk-modifying strategies designed to mitigate the risk of stroke in patients with AF.1,2 In this expert interview, Tony D Grayson and Carol Hughes highlight the role of direct […]

Ventricular tachycardia (VT) ablation presents a challenging and growing area of focus in the realm of complex ablation, with promises of improved patient’s quality of life and clinical outcomes.1,2 Classic approaches to VT ablation centered on arrhythmia induction and entrainment of the circuit in order to identify the components critical to arrhythmia propagation. Identification of mid-diastolic […]