Trending Topic

15 mins

Trending Topic

Developed by Touch
Mark CompleteCompleted
BookmarkBookmarked

Cardiovascular diseases are the most common cause of mortality and morbidity in adults worldwide.1 Coronary angiography (CAG) is the gold standard method for evaluating atherosclerotic coronary artery disease (CAD).2 It is conventionally performed via the trans-femoral (TF) route. Recently, however, the trans-radial (TR) route has become the preferred way.3 The TR route offers better procedure comfort, shorter hospitalization […]

< 1 min

Heart rate turbulence and variability in patients with ventricular arrhythmias

Federico Lombardi, Fabrizio Tundo, Abdalrahim Abukwaik, Diego Tarricone
Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Download as PDF
Published Online: Jul 27th 2018 Heart International 2007;3(1-2):51-7
Select a Section…
1

Abstract

Overview

Background. To evaluate the changes in autonomic neural control mechanisms before
malignant ventricular arrhythmias, we measured heart rate variability (HRV) and heart rate
turbulence (HRT) in patients with ventricular tachycardia or fibrillation (Group I; n=6), non sustained
ventricular tachycardia (Group II; n=32), frequent premature ventricular beats (Group III;
n=26) and with ICD implantation (Group IV; n=11).
Methods. Time domain parameters of HRV and turbulence onset (TO) and slope (TS) were calculated
on 24 hour Holter recordings. Normal values were: SDNN > 70 msec for HRV, TO <0% and TS >2.5 msec/RR-I for HRT.
Results. Whereas SDNN was within normal range and similar in all study groups, HRT parameters
were significantly different in patients who experienced VT/VF during Holter recording. Abnormal
TO and/or TS were present in 100% of Group I patients and only in about 50% of Group
II and IV. On the contrary, normal HRT parameters were present in 40-70% of Group II, III and IV
patients and none of Group I.
Conclusions. These data suggest that HRT analysis is more suitable than HRV to detect those
transient alterations in autonomic control mechanisms that are likely to play a major trigger role
in the genesis of malignant cardiac arrhythmias. (Heart International 2007; 3: 51-7)

Keywords

Sudden cardiac death, Autonomic nervous system, Risk stratification, Ventricular fibrillation, Holter recordings

2

Article Information

Correspondence

Prof. Federico Lombardi, MD, FESC Cardiologia, Dipartimento di Medicina, Chirurgia e Odontoiatria, Osp. San Paolo, Università di Milano, Via A. di Rudinì, 8, 20142 Milano – Italy, Federico.Lombardi@unimi.it

3

Further Resources

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Download as PDF
Close Popup