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The foramen ovale, an obligatory channel, allows placental oxygenated blood to directly reach the fetal arterial circulation and remains patent in 25% of the adult population.1 Patency provides a potential gateway for venous emboli to reach the arterial circulation, potentially resulting in systemic embolus or stroke (now termed ‘patent foramen ovale [PFO]-associated stroke’).2 Preventive strategies for recurrent […]

Cardiovascular Disease

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An Introduction to Cardiovascular Disease

Cardiovascular diseases (CVDs) are the number one cause of death globally, taking an estimated 17.9 million lives each year. CVDs describe a number of conditions affecting the heart and circulation, including coronary heart disease, angina, congenital heart disease, hypertension and stroke. The huge and ever-increasing burden of CVDs on individuals and healthcare systems shows the urgent ongoing need for treatments and preventive measures.

Browse the content below where leading experts discuss the latest data in video interviews and short articles from our conference hub, and browse the selection of peer-reviewed articles from our journal portfolio. If you are looking to learn more about the impact of these developments on patient outcomes, our educational activities are a great resource.

Our supporting partners do not constitute an endorsement of the content on this page.

touchVisionary Voices
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Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more effective healthcare culture.

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What if your medical degree could launch more than a clinical career? In this candid and compelling read, Dr Jon Edelson shares his lessons for early-career clinicians ready to think beyond the bedside and explore the business of medicine.

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May 2025 saw several significant developments in the field of cardiology, including new regulatory approvals, long-term clinical trial data and important findings from late-breaking studies. This roundup highlights the latest updates across structural, interventional and heart failure therapies, with implications for ...

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The ACT-EARLY clinical trial has dosed its first participant in an effort to prevent variant transthyretin amyloidosis (ATTRv) in genetically at-risk individuals. By evaluating the selective TTR stabilizer, acoramidis, in asymptomatic carriers, the study aims to delay or halt disease onset. With approximately 600 participants, ACT-EARLY marks a pivotal step toward shifting ATTRv care from reactive treatment to proactive prevention.

touchVisionary Voices
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In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.

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Findings from a Phase IIa trial presented at EAS 2025 suggest that targeting ANGPTL4 with a monoclonal antibody may significantly reduce triglycerides and remnant cholesterol in high-risk cardiovascular patients. MAR001 was well tolerated, with no serious adverse events. These results support further investigation in a larger Phase 2b study.

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The EU-funded DORIAN GRAY project, aims to uncover how cardiovascular disease contributes to mild cognitive impairment using AI and avatar technology. By integrating real-world data from over 300,000 individuals, the initiative seeks to personalize prevention strategies, enhance cognitive health, and reduce dementia risk across Europe.

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In this Q&A, we talk to Dr Nadia Chaher shares insights into her career so far, her experiences and the most exciting current innovations in cardio-imaging.

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Cardiovascular disease (CVD) continues to be the primary cause of mortality and morbidity globally with middle-aged women presenting with additional and possibly, overlooked risk factors.1 Despite several awareness programmes, there remain several gaps in the political education and representation needs ...

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For HCPs in: Europe

Learn about barriers to effective long-term weight management and pharmacological treatment options for obesity.

6 mins
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Watch a leading expert discuss the need for personalised obesity treatment including current evidence for cardiovascular outcomes.

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Cardiovascular disease (CVD) is a significant cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). An estimated 60–80% of patients with T2DM die of cardiovascular events.1,2 A bidirectional relationship has been noted between heart failure (HF) ...

5 mins
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In this engaging short animation, learn how cholesterol-lowering MTP inhibitors act to reduce cholesterol in people with homozygous familial hypercholesterolemia, and explore clinical data supporting their long-term hepatic safety.

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touchCARDIO is delighted to announce that Heart International has received an impressive new Impact Factor of 1.9 in the 2024 Journal Citation Reports (JCR). This achievement marks a notable increase from last year’s Impact Factor of 0.2 and highlights the journal’s growing influence in the cardiology field.

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This corrects the article: “Ioannou A. Evolution of Disease-modifying Therapy for Transthyretin Cardiac Amyloidosis. Heart International. 2024;18(1):30-37”. Two typography errors were included incorrectly due to an editorial error. In Table 1, “eplontersen” was incorrectly written as “eplomtersen”. This has been corrected ...

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