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Cardiovascular diseases are the most common cause of mortality and morbidity in adults worldwide.1 Coronary angiography (CAG) is the gold standard method for evaluating atherosclerotic coronary artery disease (CAD).2 It is conventionally performed via the trans-femoral (TF) route. Recently, however, the trans-radial (TR) route has become the preferred way.3 The TR route offers better procedure comfort, shorter hospitalization […]

Marked prolongation of QRS duration after initiation of dronedarone therapy

Conrad Genz, Hans D. Esperer, Alexander Schmeisser, Ruediger C. Braun-Dullaeus, Samir M. Said
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Published Online: Aug 10th 2018 Heart International 2014;9(1):33-35 DOI: https://doi.org/10.5301/HEART.2014.12491
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Abstract

Overview

Dronedarone is a relatively new antiarrhythmic drug and is held to be less proarrhythmic than comparable compounds,
although its proarrhythmia potential in humans has not been sufficiently evaluated. We describe a so far
unreported dronedarone effect, namely a significant alteration of both the morphology and the duration of the
QRS complex on the electro cardiogram in a 41-year old patient with symptomatic paroxysmal atrial fibrillation.

Keywords

Adverse drug events, Antiarrhythmic drugs, Atrial fibrillation, Dronedarone.

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Article Information

Correspondence

Samir M. Said, Otto-von-Guericke University University Hospital, Centre of Internal Medicine Division of Cardiology Leipziger Str. 44 39120 Magdeburg, Germany samir.said@med.ovgu.de

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