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Cardiovascular diseases are the most common cause of mortality and morbidity in adults worldwide.1 Coronary angiography (CAG) is the gold standard method for evaluating atherosclerotic coronary artery disease (CAD).2 It is conventionally performed via the trans-femoral (TF) route. Recently, however, the trans-radial (TR) route has become the preferred way.3 The TR route offers better procedure comfort, shorter hospitalization […]

Milind Desai, ACC 2022: VALOR-HCM trial

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Published Online: May 3rd 2022

The VALOR-HCM trial showed the benefits of  mavacamten as an alternative to surgical septal myectomy or alcohol ablation in patients with severely symptomatic obstructive hypertrophic cardiomyopathy. It was a pleasure to speak with Prof. Milind Desai (Cleveland Clinic, Cleveland, OH) about the VALOR-HCM trial including the efficacy and safety endpoints of it and what future studies of mavacamten are planned.

Questions:

  1. Could you tell us a little about the VALOR-HCM trial? (00:21)
  2. What questions remain unanswered about the health benefits of mavacamten, and what future studies are planned? (04:45)

Disclosures: Milind Desai is a consultant for Bristol Myers Squibb and Medtronic.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the American College of Cardiology Annual Meeting 2022

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