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Cardiovascular diseases are the most common cause of mortality and morbidity in adults worldwide.1 Coronary angiography (CAG) is the gold standard method for evaluating atherosclerotic coronary artery disease (CAD).2 It is conventionally performed via the trans-femoral (TF) route. Recently, however, the trans-radial (TR) route has become the preferred way.3 The TR route offers better procedure comfort, shorter hospitalization […]

Anders Holt, ESC 2022: Risk of heart failure due to NSAID usage in diabetes, a Danish cohort study

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Published Online: Sep 5th 2022

Type 2 diabetes has been linked with subclinical cardiomyopathy and kidney function decline, therefore short-term non-steroidal anti-inflammatory drug (NSAID) use could potentially lead to the development of heart failure (HF) due to aberrations in fluid balances. In this touchCARDIO interview, we speak with Dr Anders Holt (Herlev and Gentofte Hospital, Copenhagen University Hospital, Hellerup, Denmark) to discuss the purpose and outcomes of a cohort study to assess associations between short-term NSAID use and the risk of HF in Danish cohort of patients with type 2 diabetes. 

The abstract entitled ‘Non-steroidal anti-inflammatory drugs linked with heart failure in patients with diabetes’ was presented at the European Society of Cardiology (ESC) Congress 2022, 26 – 29 August 2022.

Questions:

  1. What were the aims, design and eligibility criteria of your cohort study? (0:34)
  2. What were the findings of the study both overall and among individual NSAIDs? (3:44)
  3. What patient factors were associated with increased risk of heart failure? (6:13)
  4. What are the implications of these findings for clinical practice? (10:09)

Disclosures: Anders Holt has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ESC 2022

Access more content on Heart Failure here

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