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Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Mandeep Mehra, ESC 2022: Advances in left ventricular assist devices (LVADs) for heart failure and the advantages of the HeartMate 3™ LVAD

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Published Online: Sep 9th 2022

Left ventricular assist devices (LVADs) are utilised to treat patients with heart failure, the HeartMate 3™ being an example. In this touchCARDIO interview, we speak with Dr Mandeep Mehra (Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA) to discuss the advances in LVADs and the advantages the HeartMate 3™ (HM3) LVAD holds over other LVADs.

The abstract entitled ‘5-year Survival with LVAD Therapy in MOMENTUM 3’ was presented at the European Society of Cardiology (ESC) Congress 2022, 26 – 29 August 2022.

Questions:

  1. Could you give us a brief overview of advances in left ventricular assist devices (LVADs) and their application in heart failure patients? (0:21)
  2. Please tell us a little about the HeartMate 3™ (HM3) LVAD and its advantages over other LVADs. (2:06)

Disclosures: Mandeep Mehra is a consultant for Abbott, Janssen, Mesoblast, Medtronic, Natera and Paragonix and is on the advisory board for FineHeart, Leviticus, NupulseCV and Transmedics. 

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ESC 2022

Access more content on Devices here and Heart Failure here

Additional Resources: Mehra MR, Goldstein DJ, Cleveland JC, et al. Five-Year Outcomes in Patients With Fully Magnetically Levitated vs Axial-Flow Left Ventricular Assist Devices in the MOMENTUM 3 Randomized Trial. JAMA. 2022; doi: 10.1001/jama.2022.16197.

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