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Native valve infective endocarditis (IE) is rare, with an incidence of 3–7 cases per 100,000 person-years.1,2 Cardiac structural complications from local infection extension include valvular destruction, peri-annular abscess and fistula formation. Left ventricular pseudoaneurysm (LVP) from IE is exceedingly rare, occurring in <1% of cases, and is associated with high morbidity and mortality. Diagnosis is challenging due to nonspecific symptoms […]

Clara Chow, ESC 2021 – the QUARTET Study

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Published Online: Sep 24th 2021

Dr Clara Chow (Professor of Medicine, Academic Director Westmead Applied Research Centre, University of Sydney, Sydney, Australia) kindly shared her thoughts on the limitations of current treatment paradigms for hypertension, the quad pill for hypertension, and the QUARTET study, from the virtual ESC Congress 2021.

Questions

  1. What are the limitations of current treatment paradigms for hypertension? (0.18)
  2. What is the composition of the quad pill for hypertension, and what is the rationale for its use? (1.26)
  3. What have clinical studies to date taught us about the efficacy and safety of this approach? (2.38)
  4. What were the aims, design and eligibility criteria of the QUARTET study? (3.41)
  5. What are the strengths and limitations of this study? (6.01)

Speaker disclosures: Dr Clara Chow has nothing to declare in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media and conducted by Heather Hall.

Filmed during a remote video call with Dr Clara Chow as a highlight of ESC 2021, August 2021.

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