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Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Marie-Sophie de Koning, ACC 2022: GIPS-IV: The Groningen Intervention Study For the Preservation of Cardiac Function With Sodium Thiosulfate After ST-segment Elevation Myocardial Infarction

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Published Online: May 3rd 2022

The Groningen Intervention study for the Preservation of cardiac function with STS after STEMI (GIPS-IV) trial is a double-blind, randomized, placebo-controlled, multicenter trial. touchCARDIO speaks with Dr Marie-Sophie de Koning (University of Groningen, Groningen, The Netherlands) to discuss her presentation of the GIPS-IV trial and to highlight the rationale, design, and study findings.

Questions: Marie-Sophie de Koning has nothing to disclose in relation to this video.

  1. What is the rationale for the use of hydrogen sulphide in patients after ST-segment Elevation Myocardial Infarction (STEMI)? (00:19)
  2. What are the aims and design of the GIPS-IV trial? (01:05)
  3. What are the clinical endpoints and eligibility findings of the study? (02:08)
  4. What are the study findings to date? (02:38)

Disclosures: Marie-Sophie de Koning has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the American College of Cardiology Annual Meeting 2022

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