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Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.1 High systolic blood pressure (SBP) remains one of the top risk factors for CVD burden globally.2 Despite being a modifiable risk factor, hypertension (HTN) remains largely undiagnosed and untreated due to inadequate screening, poor awareness and lack of treatment adherence.3 Globally, HTN is undiagnosed in about 46% […]

Stephen Nicholls, ESC 2021 – the HUYGENS Study

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Published Online: Sep 24th 2021

Prof. Stephen Nicholls (Professor of Cardiology, Monash University, Melbourne, Australia) kindly shared his thoughts on the impact of PCSK9 inhibitors on lipid-lowering therapy, the effects of statins on coronary atherosclerotic plaques and the HUYGENS study from the virtual ESC Congress 2021.

Questions

  1. What has been the impact of PCSK9 inhibitors on lipid-lowering therapy, and what questions remain unanswered? (0.12)
  2. What have optical coherence tomography (OCT) studies taught us about the effects of statins on coronary atherosclerotic plaques? (0.48)
  3. What were the aims and design of the HUYGENS study? (2.13)
  4. What have been the study findings to date? (2.54)
  5. What are the clinical implications of these findings? (4.23)

Speaker disclosures: Prof. Stephen Nicholls wishes to disclose research support and consulting for Amgen and Sanofi-Regeneron.

Support: Interview and filming supported by Touch Medical Media and conducted by Heather Hall.

Filmed during a remote video call with Professor Stephen Nicholls as a highlight of ESC 2021, September 2021.

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