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Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.1 High systolic blood pressure (SBP) remains one of the top risk factors for CVD burden globally.2 Despite being a modifiable risk factor, hypertension (HTN) remains largely undiagnosed and untreated due to inadequate screening, poor awareness and lack of treatment adherence.3 Globally, HTN is undiagnosed in about 46% […]

Aldo Pietro Maggioni, ESC 2019 – Oral Anticoagulants and Ischaemic Stroke in Atrial Fibrillation

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Published Online: Sep 4th 2019

We spoke to Dr Aldo Pietro Maggioni (Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) Research Center, Florence, Italy) about the key observations from his study of trends in oral anticoagulant use and the rate of ischaemic stroke in people with atrial fibrillation. He also discussed how big data can provide insight and what he expects to see from real-world observations, as well as how this may affect routine practice.

Speaker’s Disclosures: Aldo Pietro Maggioni has nothing to declare in relation to this video interview.

Questions:
1. What were the key observations in your study of trends in oral anticoagulant use and rate of ischaemic stroke over a 4-year period in 194,030 people with atrial fibrillation? (0:04)
2. How can ‘big data’ provide insight beyond randomised clinical trials and registry studies? (1:59)
3. What findings do you expect to emerge from large-scale real-world observations, and how can these findings help cardiovascular physicians in routine practice? (3:28)

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Filmed at the European Society of Cardiology (ESC) Congress 2019 in Paris, France, September 2019.

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