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Native valve infective endocarditis (IE) is rare, with an incidence of 3–7 cases per 100,000 person-years.1,2 Cardiac structural complications from local infection extension include valvular destruction, peri-annular abscess and fistula formation. Left ventricular pseudoaneurysm (LVP) from IE is exceedingly rare, occurring in <1% of cases, and is associated with high morbidity and mortality. Diagnosis is challenging due to nonspecific symptoms […]

Charalambos Antoniades, ESC 2018 – the CRISP-CT Study, Perivascular Fat and Cardiac Death

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Published Online: Aug 31st 2018

Professor Charalambos Antoniades (Professor of Cardiovascular Medicine, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK) discusses the imaging of perivascular fat and computed tomography (CT) technology, with particular emphasis on the results of the CRISP-CT study, presented at ESC 2018.

 

Filmed at ESC 2018, Munich.

View more content here.

Speaker Disclosure: Professor Charalambos Antoniades has the following disclosures in relation to this video interview: founder, shareholder and CSO of Caristo Diagnostics.

Questions:

Part 1:

1. Please describe your new computed tomography (CT) technology and how it allows perivascular fat to be imaged? (0:09)

2. What are they key results from the CRISP-CT study and how has this study validated the CT technology for the detection of perivascular fat and risk of cardiac death? (1:55)

Part 2:

3. In what way does your new CT technology represent an advancement from existing methods of detecting coronary inflammation? (0:08)

4. What do you think will be the main benefits of non-invasive imaging of perivascular fat for the treatment and management of coronary disease? (1:13)

5. What work is currently ongoing and/or needs to be done to further validate your new CT technology? (3:48)

 

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