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Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.1 High systolic blood pressure (SBP) remains one of the top risk factors for CVD burden globally.2 Despite being a modifiable risk factor, hypertension (HTN) remains largely undiagnosed and untreated due to inadequate screening, poor awareness and lack of treatment adherence.3 Globally, HTN is undiagnosed in about 46% […]

Marie-Sophie de Koning, ACC 2022: GIPS-IV: The Groningen Intervention Study For the Preservation of Cardiac Function With Sodium Thiosulfate After ST-segment Elevation Myocardial Infarction

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Published Online: May 3rd 2022

The Groningen Intervention study for the Preservation of cardiac function with STS after STEMI (GIPS-IV) trial is a double-blind, randomized, placebo-controlled, multicenter trial. touchCARDIO speaks with Dr Marie-Sophie de Koning (University of Groningen, Groningen, The Netherlands) to discuss her presentation of the GIPS-IV trial and to highlight the rationale, design, and study findings.

Questions: Marie-Sophie de Koning has nothing to disclose in relation to this video.

  1. What is the rationale for the use of hydrogen sulphide in patients after ST-segment Elevation Myocardial Infarction (STEMI)? (00:19)
  2. What are the aims and design of the GIPS-IV trial? (01:05)
  3. What are the clinical endpoints and eligibility findings of the study? (02:08)
  4. What are the study findings to date? (02:38)

Disclosures: Marie-Sophie de Koning has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the American College of Cardiology Annual Meeting 2022

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