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Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.1 High systolic blood pressure (SBP) remains one of the top risk factors for CVD burden globally.2 Despite being a modifiable risk factor, hypertension (HTN) remains largely undiagnosed and untreated due to inadequate screening, poor awareness and lack of treatment adherence.3 Globally, HTN is undiagnosed in about 46% […]

Milind Desai, ACC 2022: VALOR-HCM trial

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Published Online: May 3rd 2022

The VALOR-HCM trial showed the benefits of  mavacamten as an alternative to surgical septal myectomy or alcohol ablation in patients with severely symptomatic obstructive hypertrophic cardiomyopathy. It was a pleasure to speak with Prof. Milind Desai (Cleveland Clinic, Cleveland, OH) about the VALOR-HCM trial including the efficacy and safety endpoints of it and what future studies of mavacamten are planned.

Questions:

  1. Could you tell us a little about the VALOR-HCM trial? (00:21)
  2. What questions remain unanswered about the health benefits of mavacamten, and what future studies are planned? (04:45)

Disclosures: Milind Desai is a consultant for Bristol Myers Squibb and Medtronic.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the American College of Cardiology Annual Meeting 2022

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