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Mechanistic interpretations of sustained ventricular fibrillation: The role of mapping methodology, model and time

Johanna B Tonko, Vineesh Kappadan, Ahmed El-Medany

Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Heart International. 2026;20(1):5-19

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HEART INTERNATIONAL VOLUME 12 ISSUE 1

Atherosclerosis

The inhibitory effects of polysaccharide peptides (PsP) of Ganoderma lucidum against atherosclerosis in rats with dyslipidemia

< 1 min

Arrhythmia Interventional Cardiology

Placement Of Cardiac PacemaKEr Trial (POCKET) – rationale and design: a randomized controlled trial

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Atherosclerosis Imaging

Mild troponin I elevation does not predict ischemia on myocardial perfusion imaging

< 1 min

Cardiovascular Disease Hypertension

Role of optimal medication given to patients with hypertension and ischemic heart disease prior to an acute coronary syndrome

< 1 min

Imaging Interventional Cardiology

Calculating the 30-day survival rate in acute myocardial infarction: should we use the treatment chain or the hospital catchment model?

< 1 min

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FOREWORD – HEART INTERNATIONAL – VOLUME 20 ISSUE 1 – 2026

Magdi El-Omar

Cardiovascular care continues to evolve in response to increasingly complex clinical realities, where advances in intervention, electrophysiology and population health must be integrated with a more critical appraisal of long-held assumptions. Across disciplines, there is a growing recognition that improving outcomes depends not only on technological progress, but also on refining our understanding of mechanisms, […]

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