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Hypertension is the leading modifiable risk factor for global cardiovascular disease, responsible for an estimated 10.8 million deaths and more than 200 million disability-adjusted life years annually.1 Despite the availability of effective pharmacological and lifestyle interventions, prevalence continues to rise, particularly in low- and middle-income countries (LMICs), where over three-quarters of all cases now occur.2 The condition’s […]

HEART INTERNATIONAL – VOLUME 17, ISSUE 2 – 2023

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FOREWORD

In this issue of Heart International, we are delighted to present a collection of insightful articles that encompass a wide spectrum of topics within the field of cardiovascular medicine. As we navigate the landscape of cardiovascular disease, heart failure, preventative cardiology, interventional procedures and the latest advancements in research, we find ourselves on the cutting […]

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Review

For decades, right ventricular pacing (RVP) has been the leading pacing technique and has been proven to be effective in treating patients with symptomatic bradycardia. However, dyssynchrony caused by non-physiological ventricular activation results in pacing-induced cardiomyopathy occurs in approximately 15% of patients with >20% ventricular pacing after 5 years.1 Pacing of the right ventricular septum has […]

With the global increase in life expectancy, the proportion of elderly people in the community is expected to increase gradually. This is referred to as the ‘Coming of the Gray Dawn’ or the ‘Gray Wave’, and highlights the need for current day healthcare professionals to better understand the specific disease processes that occur in the […]

Diabetes mellitus (DM) is strongly associated with severe macro- and micro-vascular complications; it is also proven to be a strong independent risk factor for developing heart failure (HF).1 In fact, the prevalence of DM is reported to be as high as 20% amongst patients with HF compared with 5–6% in the general population.2 Recent studies have […]

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Holly Morgan, Saad M Ezad, Haseeb Rahman

Cardiac complications constitute a common cause of morbidity and mortality in the perioperative period, contributing to over a third of perioperative deaths.1 More than 230 million major surgeries are performed annually worldwide, with older patients representing an increasing proportion of the surgical population; a group with a significant burden of cardiovascular risk factors and a higher […]

17 mins
Michael Albosta, Jelani K Grant, Erin D Michos

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality both in the US and worldwide.1 There is substantial evidence from genetic, observational and interventional studies that low-density lipoprotein cholesterol (LDL-C) is causally related to the development of ASCVD in a dose-dependent fashion.2,3 Statins have been shown to substantially lower LDL-C and form the cornerstone of […]

Heart failure (HF), a prevalent disease, is the common final pathway of several conditions, which result in the activation of numerous neurohumoral pathways. Cardiorenal interaction plays an essential role in the progression of the disease, and the use of diuretics is a cornerstone in the treatment of hypervolemic patients, especially in acute decompensated HF (ADHF).1 The […]

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