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Hypertension is the leading modifiable risk factor for global cardiovascular disease, responsible for an estimated 10.8 million deaths and more than 200 million disability-adjusted life years annually.1 Despite the availability of effective pharmacological and lifestyle interventions, prevalence continues to rise, particularly in low- and middle-income countries (LMICs), where over three-quarters of all cases now occur.2 The condition’s […]

62/Repeat ablations and patient characteristics in paroxysmal supraventricular tachycardia patients age <65 in the United States

NC Sacks (Presenting Author) – Precision Xtract, Boston, MA, USA; S Green – Precision Health Economics, Los Angeles, CA, USA; MT Preib – Precision Xtract, Boston, MA, USA; PL Cyr – Precision Xtract, Boston, MA, USA; DR Wood – Milestone Pharmaceuticals, Montreal, QC, Canada; S Pokorney – Duke University Medical Center, Durham, NC, USA
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Published Online: Oct 4th 2008 European Journal of Arrhythmia & Electrophysiology. 2019;5(Suppl. 1):abstr62
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Article

Background: Catheter ablation for paroxysmal supraventricular tachycardia (PSVT) is potentially curative but little is known about the frequency or timing of repeat ablations.

Purpose: To characterise repeat ablations in patients <65 years with PSVT.

Methods: Retrospective study using demographic, enrolment, and claims data from the IBM MarketScan® research database to identify patients <65 years with an initial catheter ablation for PSVT (ICD-9: 427.0; ICD-10: I47.1) between January 1, 2009 and December 31, 2015. Patients were required to be observable for 1 year before and after index ablation; a subset of patients was followed for up to 7 years post index. Primary outcome was repeat ablation within 1 year; Secondary outcome was repeat ablation in all follow-up. Logistic regression was used to assess odds of re-ablation.

Results: 20,649 patients meet the study criteria; mean age was 44 years (SD: 15.6), 59.1% were female sex. 1,520 (7.4%) had a second ablation within 12 months of the first, and the majority were within 6 months (n=1,067; 70.2%). Re-ablation rates increased to 12.4% in patients observable 2 years post-index and to 14.9% by 7 years post-index ablation (Figure 1). Male sex was significantly associated with higher re-ablation rates (8.6% versus 6.5% p<0.0001); age was not significantly associated.

Conclusion: Approximately, 1 in 8 patients that has an ablation for PSVT goes on to have a second ablation for PSVT within 2 years. More data is needed on predictors of patients that have >1 ablation for PSVT, as well as the optimal management strategy for these patients.

 

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