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Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Thomas Lüscher, ESC 2020 – Gut Microbiota and Cardiovascular Disease

15.37 mins
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Published Online: Sep 9th 2020

We caught up with Prof Thomas Lüscher (Royal Brompton and Harefield Hospital and Imperial College, London, UK) on the association between gut microbiota, the gut microbiome and cardiovascular disease.

Questions

  1. What is known about the association between gut microbiome changes and cardiovascular disease? (0.38)
  2. Which gut microbiota–dependent metabolites are involved in the pathogenesis of cardiovascular disease? (2.49)
  3. What novel therapeutic strategies are being investigated for targeting the gut microbiome to improve cardiovascular outcomes? (5.44)
  4. Could you give us an overview about the most important recent studies? (9.44)
  5. What are the major gaps in our knowledge and what future studies are planned? (12.13)

Speaker disclosures: Professor Thomas Lüscher has nothing to declare in relation to this video interview.

Support: Commissioned, edited and funded by Touch Medical Media.

Filmed during a remote video call with Professor Thomas Lüscher, September 2020.

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