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Native valve infective endocarditis (IE) is rare, with an incidence of 3–7 cases per 100,000 person-years.1,2 Cardiac structural complications from local infection extension include valvular destruction, peri-annular abscess and fistula formation. Left ventricular pseudoaneurysm (LVP) from IE is exceedingly rare, occurring in <1% of cases, and is associated with high morbidity and mortality. Diagnosis is challenging due to nonspecific symptoms […]

Charalambos Antoniades, ESC 2021 – High-sensitivity C-reactive Protein, Perivascular Adipose Tissue and Atherosclerosis

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Published Online: Sep 24th 2021

Prof. Charalambos Antoniades (Professor of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK) kindly shared his thoughts on the use of high-sensitivity C-reactive protein as a biomarker in clinical decision making, and the role of perivascular adipose tissue in the pathogenesis of atherosclerosis from the virtual ESC Congress 2021.

Questions

  1. What is the rationale for the use of high-sensitivity C-reactive protein (hsCRP) as a biomarker in clinical decision making and what are its limitations? (0.15)
  2. What have we learned about the role of perivascular adipose tissue in the pathogenesis of atherosclerosis? (1.08)

Speaker disclosures: Prof. Charalambos Antoniades is founder, shareholder and director of Caristo Diagtnostics. 

Support: Interview and filming supported by Touch Medical Media and conducted by Heather Hall.

Filmed during a remote video call with Prof. Charalambos Antoniades as a highlight of ESC 2021, August 2021.

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