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Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Charalambos Antoniades, ESC 2021 – High-sensitivity C-reactive Protein, Perivascular Adipose Tissue and Atherosclerosis

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Published Online: Sep 24th 2021

Prof. Charalambos Antoniades (Professor of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK) kindly shared his thoughts on the use of high-sensitivity C-reactive protein as a biomarker in clinical decision making, and the role of perivascular adipose tissue in the pathogenesis of atherosclerosis from the virtual ESC Congress 2021.

Questions

  1. What is the rationale for the use of high-sensitivity C-reactive protein (hsCRP) as a biomarker in clinical decision making and what are its limitations? (0.15)
  2. What have we learned about the role of perivascular adipose tissue in the pathogenesis of atherosclerosis? (1.08)

Speaker disclosures: Prof. Charalambos Antoniades is founder, shareholder and director of Caristo Diagtnostics. 

Support: Interview and filming supported by Touch Medical Media and conducted by Heather Hall.

Filmed during a remote video call with Prof. Charalambos Antoniades as a highlight of ESC 2021, August 2021.

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