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Hypertension is the leading modifiable risk factor for global cardiovascular disease, responsible for an estimated 10.8 million deaths and more than 200 million disability-adjusted life years annually.1 Despite the availability of effective pharmacological and lifestyle interventions, prevalence continues to rise, particularly in low- and middle-income countries (LMICs), where over three-quarters of all cases now occur.2 The condition’s […]

Charalambos Antoniades, ESC 2021 – High-sensitivity C-reactive Protein, Perivascular Adipose Tissue and Atherosclerosis

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Published Online: Sep 24th 2021

Prof. Charalambos Antoniades (Professor of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK) kindly shared his thoughts on the use of high-sensitivity C-reactive protein as a biomarker in clinical decision making, and the role of perivascular adipose tissue in the pathogenesis of atherosclerosis from the virtual ESC Congress 2021.

Questions

  1. What is the rationale for the use of high-sensitivity C-reactive protein (hsCRP) as a biomarker in clinical decision making and what are its limitations? (0.15)
  2. What have we learned about the role of perivascular adipose tissue in the pathogenesis of atherosclerosis? (1.08)

Speaker disclosures: Prof. Charalambos Antoniades is founder, shareholder and director of Caristo Diagtnostics. 

Support: Interview and filming supported by Touch Medical Media and conducted by Heather Hall.

Filmed during a remote video call with Prof. Charalambos Antoniades as a highlight of ESC 2021, August 2021.

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