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Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Jagmeet Singh, HRS 2019 – Findings from the MADIT CHIC Study

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Published Online: Jun 14th 2019

We spoke to Dr Jagmeet Singh (Associate Chief, Cardiology Division, Massachusetts General Hospital, Boston, MA, USA) at the recent Heart Rhythm 2019 about the findings of the Multicenter Automatic Defibrillator Implantation Trial – Chemotherapy-induced Cardiomyopathy (MADIT CHIC) and how they might be interpreted in practice. Dr Singh also touches on the current unmet needs in chemotherapy-induced cardiomyopathy.

Filmed at Heart Rhythm 2019, San Francisco, CA, USA.

Speaker’s Disclosures: Jagmeet Singh consults for Abbott, Back Beat, Biotronik, Boston Scientific, EBR, Impulse Dynamics, Medtronic, Microport and Toray, and received research grants from Abbott and Boston Scientific. The study discussed was supported by an investigator-initiated research grant from Boston Scientific.

Questions:
1. What were the findings of the Multicenter Automatic Defibrillator Implantation Trial ‒ Chemotherapy-induced Cardiomyopathy (MADIT CHIC) study? (0:09)
2. How should these findings be interpreted in practice and how can they help optimise treatment selection in this patient population? (1:49)
3. What are the current unmet needs in chemotherapy-induced cardiomyopathy? (2:35)

touchCARDIO.com is an independent information resource supporting physicians, clinicians and leading industry professionals in continuously developing their knowledge, effectiveness and productivity, via free-to-access content in multimedia formats.

Filmed in partnership with Arrhythmia Alliance.

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