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Mechanistic interpretations of sustained ventricular fibrillation: The role of mapping methodology, model and time

Johanna B Tonko, Vineesh Kappadan, Ahmed El-Medany

Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Heart International. 2026;20(1):5-19

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HEART INTERNATIONAL VOLUME 9 ISSUE 1

Arrhythmia Atrial Fibrillation

Marked prolongation of QRS duration after initiation of dronedarone therapy

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Hypertension

Intravenous sildenafil in right ventricular dysfunction with pulmonary hypertension following a heart transplant

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Atherosclerosis Imaging

Nuclear stress perfusion imaging versus computed tomography coronary angiography for identifying patients with obstructive coronary artery disease as defined by conventional angiography: insights from the CorE-64 multicenter study

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Imaging Interventional Cardiology

The double helix angiography of right coronary arteries: false lumen stenting of a type F right coronary artery spiral dissection with late recanalization of the true lumen and occlusion of the stented false lumen

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Arrhythmia

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures

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Arrhythmia

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of clinical results

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Arrhythmia Interventional Cardiology

An unusual cause of ventricular tachycardia: Port-A-Cath fracture and embolization into the pulmonary artery

< 1 min

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FOREWORD – HEART INTERNATIONAL – VOLUME 20 ISSUE 1 – 2026

Magdi El-Omar

Cardiovascular care continues to evolve in response to increasingly complex clinical realities, where advances in intervention, electrophysiology and population health must be integrated with a more critical appraisal of long-held assumptions. Across disciplines, there is a growing recognition that improving outcomes depends not only on technological progress, but also on refining our understanding of mechanisms, […]

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