This website is intended for healthcare professionals only

Trending Topic

Doctor holding glowing holographic human anatomical heart. Medical illustration, heart diseases, heart health
9 mins

Trending Topic

Developed by Touch
Mark CompleteCompleted
BookmarkBookmarked

Native valve infective endocarditis (IE) is rare, with an incidence of 3–7 cases per 100,000 person-years.1,2 Cardiac structural complications from local infection extension include valvular destruction, peri-annular abscess and fistula formation. Left ventricular pseudoaneurysm (LVP) from IE is exceedingly rare, occurring in <1% of cases, and is associated with high morbidity and mortality. Diagnosis is challenging due to nonspecific symptoms […]

Gilles Montalescot, ESC 2021 – the QUORUM Clinical Study

8.03 mins
Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Published Online: Sep 9th 2021

Prof. Gilles Montalescot (Professor, Pitié-Salpêtrière Hospital, Paris, France) kindly shared his thoughts on the difficulty of treating heart failure after acute myocardial infarction, the use of firibastat and the QUORUM clinical study (NCT03715998) from the virtual ESC Congress 2021.

Questions

  1. Why does heart failure after acute myocardial infarction remain so challenging to treat? (0.19)
  2. Could you tell us a little about firibastat and the rationale for its potential use in heart failure post myocardial infarction? (1.44)
  3. What were the aims and design of the QUORUM clinical study? (3.00)
  4. What were the efficacy and safety endpoints and how well were they achieved? (4.36)
  5. What will be the clinical impact of these findings? (7.13)

Speaker disclosures: Prof. Gilles Montalescot declares research funds for the Institution or fees from Abbott, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Bristol-Myers Squibb, Cell Prothera, CSL Behring, Europa, Idorsia, IRIS -Servier, Medtronic, MSD, Novartis, Pfizer, Quantum Genomics and Sanofi-Aventis.

Support: Interview and filming supported by Touch Medical Media and conducted by Heather Hall.

Filmed during a remote video call with Prof. Gilles Montalescot as a highlight of ESC 2021, August 2021.

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Close Popup