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Ventricular fibrillation (VF) is characterized by rapid (>300 beats a per minute), irregular electrical activation with variable electrocardiographic waveforms that prevents coordinated myocardial contraction, resulting in immediate loss of cardiac output.1 It most commonly occurs in the context of coronary artery disease.2,3 Resuscitation efforts are critically time-dependent: with each minute of untreated VF, the survival rate declines […]

Justin Ezekowitz, ACC 2022: SODIUM-HF: Study of dietary intervention under 100 Mmol in heart failure

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Published Online: May 3rd 2022

The SODIUM-HF trial tested whether or not a reduction in dietary sodium reduces the incidence of heart failure. touchCARDIO speaks with Prof. Justin Ezekowitz (University of Alberta, Edmonton, Canada) to discuss his presentation on the SODIUM-HF study on the effect of sodium restriction on mortality and morbidity in patients with heart failure.

The presentation entitled ‘SODIUM-HF: Study of Dietary Intervention Under 100 Mmol in Heart Failure’ was presented at the American College of Cardiology Annual Meeting 2022, April 02-04, 2022

Questions:

  1. What is currently known about the effect of sodium restriction on mortality and morbidity in patients with heart failure? (00:23)
  2. What were the aims and design of the SODIUM-HF study? (01:04)
  3. What were the primary and secondary endpoints, and how well were they achieved? (02:18)
  4. Which patients were most likely to benefit from this intervention? (04:25)
  5. On the basis of these findings, what are your recommendations for clinical practice, and what further research is needed? (05:57)

Disclosures: Justin Ezekowitz is a consultant for American Regent, Amgen, AstraZeneca, Bayer, Bristol-Meyers Squibb, Merck, Sanofi and Servier and received grants/research support from American Regent, Amgen, AstraZeneca, Bayer, Bristol-Meyers Squibb, Merck, Sanofi, Servier, Ortho-Biotech/Johnson & Johnson and Eko

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the American College of Cardiology Annual Meeting 2022

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