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Native valve infective endocarditis (IE) is rare, with an incidence of 3–7 cases per 100,000 person-years.1,2 Cardiac structural complications from local infection extension include valvular destruction, peri-annular abscess and fistula formation. Left ventricular pseudoaneurysm (LVP) from IE is exceedingly rare, occurring in <1% of cases, and is associated with high morbidity and mortality. Diagnosis is challenging due to nonspecific symptoms […]

Justin Ezekowitz, ACC 2022: SODIUM-HF: Study of dietary intervention under 100 Mmol in heart failure

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Published Online: May 3rd 2022

The SODIUM-HF trial tested whether or not a reduction in dietary sodium reduces the incidence of heart failure. touchCARDIO speaks with Prof. Justin Ezekowitz (University of Alberta, Edmonton, Canada) to discuss his presentation on the SODIUM-HF study on the effect of sodium restriction on mortality and morbidity in patients with heart failure.

The presentation entitled ‘SODIUM-HF: Study of Dietary Intervention Under 100 Mmol in Heart Failure’ was presented at the American College of Cardiology Annual Meeting 2022, April 02-04, 2022

Questions:

  1. What is currently known about the effect of sodium restriction on mortality and morbidity in patients with heart failure? (00:23)
  2. What were the aims and design of the SODIUM-HF study? (01:04)
  3. What were the primary and secondary endpoints, and how well were they achieved? (02:18)
  4. Which patients were most likely to benefit from this intervention? (04:25)
  5. On the basis of these findings, what are your recommendations for clinical practice, and what further research is needed? (05:57)

Disclosures: Justin Ezekowitz is a consultant for American Regent, Amgen, AstraZeneca, Bayer, Bristol-Meyers Squibb, Merck, Sanofi and Servier and received grants/research support from American Regent, Amgen, AstraZeneca, Bayer, Bristol-Meyers Squibb, Merck, Sanofi, Servier, Ortho-Biotech/Johnson & Johnson and Eko

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the American College of Cardiology Annual Meeting 2022

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